Survivor (n = 52) | Non-survivor (n = 49) | P value | ||
---|---|---|---|---|
IL-6 (pg/ml) | t0 | 104.5; 34.0 to 430.0 | 249.4; 96.5 to 460.2 | 0.099 |
t48 | 21.0; 8.0 to 46.0 | 82.1; 37.4 to 188.5 | 0.001** | |
t120 | 17.2; 8.9 to 38.3 | 71.6; 15.7 to 107.1 | 0.01* | |
P value | t0-t48-t120 | < 0.001*** | 0.005** | |
sICAM-1 (ng/ml) | t0 | 447.5; 323.14 to 663.6 | 399.8; 327.9 to 655.4 | 0.841 |
t48 | 434.1; 308.6 to 613.6 | 683.2; 348.3 to 1003.7 | 0.067 | |
t120 | 467.8; 320.4 to 593.0 | 630.2; 419.2 to 933.3 | 0.083 | |
P value | t0-t48-t120 | 0.432 | 0.829 | |
sVCAM-1 (ng/ml) | t0 | 1146.3; 911.3 to 1975.7 | 1227.5; 857.2 to 2242.5 | 0.837 |
t48 | 882.0; 569.6 to 1236.1 | 1275.1; 1040.0 to 2799.2 | 0.027* | |
t120 | 748.5; 639.1 to 1202.6 | 1685.5; 958.7 to 2201.2 | 0.021* | |
P value | t0-t48-t120 | 0.097 | 0.505 | |
Total CK-18 (U/l) | t0 | 1581.9; 1030.0 to 2152.0 | 2006.5; 1169.9 to 4611.6 | 0.038* |
t48 | 1579.5; 1359.8 to 2058.7 | 2007.1; 1239.0 to 4488.8 | 0.212 | |
t120 | 1829.6; 1581.9 to 2076.9 | 2533.0; 1675.2 to 3535.5 | 0.073 | |
P value | t0-t48-t120 | 0.396 | 0.814 | |
CK-18 fragments (U/l) | t0 | 357.7; 248.8 to 554.8 | 475.4; 301.5 to 1028.2 | 0.035* |
t48 | 355.4; 229.0 to 455.46 | 603.6; 410.7 to 973.5 | 0.007** | |
t120 | 324.6; 283.7 to 499.9 | 508.5; 314.8 to 881.3 | 0.108 | |
P value | t0-t48-t120 | 0.717 | 0.939 | |
Ratio | t0 | 0.3; 0.16 to 0.33 | 0.2; 0.12 to 0.36 | 0.436 |
t48 | 0.2; 0.15 to 0.30 | 0.3; 0.15 to 0.35 | 0.651 | |
t120 | 0.2; 0.15 to 0.27 | 0.3; 0.15 to 0.36 | 0.534 | |
P value | t0-t48-t120 | 0.405 | 0.939 |