| | |
Survivor (n = 52)
|
Non-survivor (n = 49)
|
P value
|
|---|
|
IL-6 (pg/ml)
|
t0
|
104.5; 34.0 to 430.0
|
249.4; 96.5 to 460.2
|
0.099
|
| |
t48
|
21.0; 8.0 to 46.0
|
82.1; 37.4 to 188.5
|
0.001**
|
| |
t120
|
17.2; 8.9 to 38.3
|
71.6; 15.7 to 107.1
|
0.01*
|
|
P value
|
t0-t48-t120
|
< 0.001***
|
0.005**
| |
|
sICAM-1 (ng/ml)
|
t0
|
447.5; 323.14 to 663.6
|
399.8; 327.9 to 655.4
|
0.841
|
| |
t48
|
434.1; 308.6 to 613.6
|
683.2; 348.3 to 1003.7
|
0.067
|
| |
t120
|
467.8; 320.4 to 593.0
|
630.2; 419.2 to 933.3
|
0.083
|
|
P value
|
t0-t48-t120
|
0.432
|
0.829
| |
|
sVCAM-1 (ng/ml)
|
t0
|
1146.3; 911.3 to 1975.7
|
1227.5; 857.2 to 2242.5
|
0.837
|
| |
t48
|
882.0; 569.6 to 1236.1
|
1275.1; 1040.0 to 2799.2
|
0.027*
|
| |
t120
|
748.5; 639.1 to 1202.6
|
1685.5; 958.7 to 2201.2
|
0.021*
|
|
P value
|
t0-t48-t120
|
0.097
|
0.505
| |
|
Total CK-18 (U/l)
|
t0
|
1581.9; 1030.0 to 2152.0
|
2006.5; 1169.9 to 4611.6
|
0.038*
|
| |
t48
|
1579.5; 1359.8 to 2058.7
|
2007.1; 1239.0 to 4488.8
|
0.212
|
| |
t120
|
1829.6; 1581.9 to 2076.9
|
2533.0; 1675.2 to 3535.5
|
0.073
|
|
P value
|
t0-t48-t120
|
0.396
|
0.814
| |
|
CK-18 fragments (U/l)
|
t0
|
357.7; 248.8 to 554.8
|
475.4; 301.5 to 1028.2
|
0.035*
|
| |
t48
|
355.4; 229.0 to 455.46
|
603.6; 410.7 to 973.5
|
0.007**
|
| |
t120
|
324.6; 283.7 to 499.9
|
508.5; 314.8 to 881.3
|
0.108
|
|
P value
|
t0-t48-t120
|
0.717
|
0.939
| |
|
Ratio
|
t0
|
0.3; 0.16 to 0.33
|
0.2; 0.12 to 0.36
|
0.436
|
| |
t48
|
0.2; 0.15 to 0.30
|
0.3; 0.15 to 0.35
|
0.651
|
| |
t120
|
0.2; 0.15 to 0.27
|
0.3; 0.15 to 0.36
|
0.534
|
|
P value
|
t0-t48-t120
|
0.405
|
0.939
| |
- Data are presented by median and interquartile range (Q1 to Q3).
- CK = cytokeratin; sICAM = soluble intercellular adhesion molecule-1; sVCAM = soluble vascular cell adhesion molecule-1.
- * P < 0.05; ** P < 0.01; *** P < 0.001.
