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Table 5 Adjusted ICU and hospital mortality by severity of hypoglycemia in patients with a primary septic diagnosis

From: The impact of early hypoglycemia and blood glucose variability on outcome in critical illness

Blood glucose category

(mmol/L)

ICU mortality

Adjusted OR§ (95% CI)

Hospital mortality

Adjusted OR‡ (95% CI)

<2.0

4.8 (3.3 to 7.0)

3.8 (2.6 to 5.6)

2.1–2.4

2.4 (1.6 to 3.6)

2.1 (1.4 to 3.1)

2.5–2.9

1.9 (1.4 to 2.6)

1.7 (1.3 to 2.4)

3.0–3.4

2.0 (1.5 to 2.5)

1.8 (1.4 to 2.3)

3.5–3.9

1.3 (1.0 to 1.6)

1.3 (1.0 to 1.6)

4.0–4.4

1.0 (0.8 to 1.2)

1.0 (0.8 to 1.2)

≥ 4.5 ¶

1.0

1.0

  1. APACHE = Acute Physiology and Chronic Health Evaluation; AuROC = area under the receiver operator characteristic curve; CI = confidence interval; ICU = intensive care unit; OR = odds ratio.
  2. ¶ Reference variable
  3. § Goodness-of-fit, P = 1.0; AuROC 0.85.
  4. ‡ Goodness-of-fit, P = 1.0; AuROC 0.82.
  5. §‡ Covariate adjustment for age, sex, surgical status, primary diagnosis, co-morbid illness, non-age-related APACHE II score, mechanical ventilation, acute kidney injury, year, and hospital site.
  6. For conversion of blood glucose from SI to conventional units divide by 0.05551.
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Critical Care

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