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Table 4 Summary of crude and adjusted ICU and hospital mortality stratified by occurrence of hypoglycemia, and by blood glucose variability, hypoglycemia or neither

From: The impact of early hypoglycemia and blood glucose variability on outcome in critical illness

Blood glucose Incidence
(%)
ICU mortality
OR (95% CI)
Hospital mortality
OR (95% CI)
   Crude Adjusted Crude> Adjusted§
Early hypoglycemia      
   Two episodes 1409 (2.1) 3.3 (2.9 to 3.7) 2.4 (2.0 to 2.8) 2.7 (2.4 to 3.0) 2.2 (1.9 to 2.5)
   One episode only 7713 (11.7) 1.9 (1.8 to 2.1) 1.3 (1.2 to 1.4) 1.7 (1.6 to 1.8) 1.2 (1.1 to 1.3)
   No hypoglycemia 57062 (86.2) 1.0 1.0 1.0 1.0
BG variability      
   BG variability 1913 (2.9) 2.7 (2.4 to 3.0) 1.5 (1.4 to 1.6) 2.4 (2.1 to 2.6) 1.4 (1.3 to 1.5)
   Hypoglycemia 7209 (10.97) 2.0 (1.8 to 2.1) 1.2 (1.1 to 1.4) 1.7 (1.6 to 1.8) 1.2 (1.0 to 1.4)
   Neither 57062 (86.2) 1.0 1.0 1.0 1.0
  1. APACHE = Acute Physiology and Chronic Health Evaluation; AuROC = area under the receiver operator characteristic curve; BG = blood glucose; CI = confidence interval; ICU = intensive care unit; OR = odds ratio.
  2. ¶Reference variable
  3. ‡ Goodness-of-fit, P = 1.0; AuROC 0.89.
  4. § Goodness-of-fit, P = 1.0; AuROC 0.87.
  5. † Goodness-of-fit, P = 1.0; AuROC 0.89.
  6. □ Goodness-of-fit, P = 1.0; AuROC 0.87.
  7. §‡□† Covariate adjustment for age, sex, surgical status, primary diagnosis, co-morbid illness, non-age-related APACHE II score, mechanical ventilation, acute kidney injury, year, and hospital site.