Skip to main content

Table 2 Variables used in bivariate analysis

From: Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort

Age (years)

Pre-treatment APACHE II score

Number and type of organ dysfunctions at baseline

Time (hours) from sepsis-induced organ dysfunction to DrotAA administration

Baseline vasopressor status (on vasopressors or not on vasopressors)

Baseline ventilator status (ventilated or not ventilated)

Baseline laboratory values and changes over time:

   • platelet count

   • serum creatinine

   • protein C

   • prothrombin time

Baseline and Day 1 SOFA scores

Study site participation in PROWESS [19] (participated in PROWESS or did not participate in PROWESS)

  1. APACHE = Acute Physiologic and Chronic Health Evaluation; DrotAA = Drotrecogin alfa activated; PROWESS = Recombinant human activated protein C worldwide evaluation in severe sepsis; SOFA = Sequential Organ Failure Assessment.
Back to article page

Critical Care

ISSN: 1364-8535