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Table 3 Epithelial cell apoptosis

From: Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis

Groups

Lung

Kidney

Liver

Villi

C-SAL

0.0 (0 to 1)

0.0 (0 to 1)

0.0 (0 to 1)

0.0 (0 to 1)

C-Gln

0.0 (0 to 1)

0.5 (0 to 1)

0.5 (0 to 1)

0.0 (0 to 1)

CLP-SAL

2.5 (2 to 4)*

2.0 (2 to 3)*

2.0 (2 to 3)*

3.5 (3 to 4)*

CLP-Gln

1.5 (1 to 2)* #

1.0 (1 to 1)* #

0.5 (0 to 1)

0.0 (0 to 1)

  1. Values are median (25th to 75th percentile) of five animals in each group. A five-point semiquantitative severity-based scoring system was used. The apoptotic findings were graded as: 0 = normal lung parenchyma; 1 = 1 to 25%; 2 = 26 to 50%; 3 = 51 to 75%; 4 = 76 to 100% of examined tissue. Sepsis was induced by cecal ligation and puncture surgery (CLP). A sham-operated group was used as control group (C) for animals undergoing CLP. One hour after surgery, C and CLP groups were further randomized into subgroups receiving saline (SAL) or glutamine (Gln). *Significantly different from C group (P < 0.05). #Significantly different from CLP-SAL group (P < 0.05).