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Table 4 Performance characteristics of APACHE II, SAPS II and ICNARC outcome prediction models

From: Outcomes following oesophagectomy in patients with oesophageal cancer: a secondary analysis of the ICNARC Case Mix Programme Database

MODEL

APACHE II

ICNARC

SAPS II

Eligible admissions, n (%)

5767 (79.8)

5767 (79.8)

5767 (79.8)

Observed mortality, n (%)

613 (10.6)

613 (10.6)

608 (10.5)

Predicted mortality, n (%)

782.8 (13.6)

729.0 (12.6)

567.0 (9.8)

AUC (95% CI)

0.63

(0.61 to 0.65)

0.67

(0.65 to 0.69)

0.65

(0.63 to 0.67)

Hosmer-Lemeshow C*

   

   Chi-squared (10)

90.8

29.6

295.7

   P value

< 0.001

0.001

< 0.001

Cox's calibration regression

   

   Intercept (95% CI)

-1.01

(-1.22 to -0.80)

-0.42

(-0.64 to -0.20)

-1.12

(-1.30 to -0.95)

   Slope (95% CI)

0.59

(0.48 to 0.69)

0.88

(0.77 to 1.00)

0.40

(0.33 to 0.47)

   Chi-squared (2)

106.4

27.9

291.4

   P value

< 0.001

< 0.001

< 0.001

Brier's score

0.097

0.091

0.101

  1. The analysis is performed on those individuals meeting criteria for all three of the models.
  2. APACHE = Acute Physiology And Chronic Health Evaluation; AUC = area under the receiver operating characteristic curve; CI = confidence interval; ICNARC = Intensive Care National Audit & Research Centre; SAPS = Simplified Acute Physiology Score.