Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury

Table 4 Unadjusted and covariate adjusted analysis for ICU mortality in CRRT patients

CRRT	Unadjusted analysis			Covariate adjusted analysis
	OR	95% CI	P	OR	95% CI	P
Male sex	1.47	0.91 to 2.37	0.097	1.86	1.11 to 3.12	0.019
Age (10-year increments)	1.34	1.17 to 1.52	< 0.001	1.42	1.22 to 1.64	< 0.001
SOFA at RRT initiation	1.18	1.09 to 1.28	< 0.001	1.20	1.10 to 1.30	< 0.001
Creatinine at RRT initiation (μmol/L)	0.85	0.76 to 0.95	0.005	0.79	0.69 to 0.90	0.001
Downtime	0.90	0.80 to 1.01	0.081	0.95	0.83 to 1.07	0.386
More-intensive (≥ 35 ml/kg/hour)	1.41	0.83 to 2.38	0.204	1.21	0.66 to 2.21	0.537

CI = confidence interval; CRRT = continuous renal replacement therapy; ICU = intensive care unit; OR = odds ratio; RRT = renal replacement therapy; SOFA = sequential organ failure assessment.

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