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Table 1 Characteristics of the study patients according to type of ICU admission

From: Markers of collagen synthesis and degradation are increased in serum in severe sepsis: a longitudinal study of 44 patients

 

Surgical patients (25)

Medical patients (19)

P value

All (n = 44)

Age, years

63 (57 to 68)

63 (56 to 74)

0.9

63 (56 to 71)

Body mass index, kg/m2

26 (24 to 32)

26 (24 to 30)

0.8

26 (24 to 32)

Male sex

15

14

0.3

29 (66%)

Chronic diseases

    

- Ischaemic heart disease

2

7

 

9 (20%)

- Arteriosclerosis obliterans

2

2

 

4 (9%)

- Diabetes

5

5

 

10 (23%)

- Chronic obstructive pulmonary disease

1

4

 

5 (11%)

- Asthma

2

2

 

4 (9%)

- Inflammatory disease (inflammatory bowel disease, vasculitis or rheumatoid diseases.)

0

0

 

0

Focus of infection

    

-Lungs

5

13

 

18

-Intra-abdominal

14

2

 

16

-Urinary

1

0

 

1

-Primary blood

2

1

 

3

-Other

3

3

 

6

Positive blood culture

8

4

0.8

13

Hydrocortisone therapy

19

13

0.6

32 (73%)

Noradrenaline

22

16

1.0

38 (86%)

-maximum rate, μg/kg/minute

0.44 (0.29 to 1)

0.24(0.12 to 1.14)

0.3

0.42(0.19 to 1)

Adrenaline

0

1

0.4

1 (2%)

Vasopressin and analogues

3

3

1.0

6 (14%)

Activated protein C

2

4

0.4

6 (14%)

Length of stay at the intensive care unit

7 (4 to 12)

5 (4 to 12)

0.7

7 (4 to 12)

APACHE II

24 (23 to 29)

26 (22 to 30)

0.7

26 (22 to 30)

Organ failure

18

12

0.5

30 (68%)

SOFA

8 (6 to 11)

8 (7 to 11)

0.9

8 (6 to 12)

Lung spesific SOFA score even once three to four

16

10

0.4

26

Mortality during the stay at the intensive care unit

6

3

0.5

9 (21%)

Mortality (30-days)

7

4

0.6

11(25%)

  1. Data is expressed as medians and 25th to 75th percentile or with frequencies and percentages.
  2. APACHE II = acute physiology and chronic health evaluation II; SOFA = sequential organ failure assessment.