Table 2 Summary of illness severity and selected laboratory values by age strata
Characteristic | Total (n = 120,123) | Age strata | P value | |||
|---|---|---|---|---|---|---|
|  |  | 18 to 40 years (n = 16,732) | 40.1 to 64.9 years (n = 42,285) | 65 to 79.9 years (n = 45,466) | ≥ 80 years (n = 15,640) |  |
Illness severity scores | Â | Â | Â | Â | Â | Â |
   APACHE II | 16.9 (7.7) | 13.0 (7.4) | 15.3 (7.6) | 18.7 (7.2) | 19.8 (7.1) | <0.001 |
   Nonage-related APACHEa | 13.3 (7.3) | 13.1 (7.4) | 13.1 (7.6) | 13.4 (7.2) | 13.8 (7.1) | <0.001 |
   APACHE III | 55.1 (27.5) | 42.3 (26.8) | 49.4 (27.2) | 60.8 (25.6) | 67.5 (25.0) | <0.001 |
Mechanical ventilation (%) | 52.0 | 52.9 | 53.7 | 53.1 | 43.7 | <0.001 |
Creatinine (μmol/l) | 90 (68 to 130) | 75 (56 to 98) | 80 (61 to 111) | 98 (71 to 141) | 110 (80 to 160) | <0.001 |
Urea (mmol/l) | 6.6 (4.6 to 10.8) | 4.5 (3.2 to 6.4) | 5.9 (4.2 to 9.0) | 7.6 (5.4 to 12) | 9.4 (6.5 to 14.7) | <0.001 |
Urine output (l/24 hours) | 1.9 (1.3 to 2.7) | 2.3 (1.5 to 3.4) | 2.0 (1.3 to 2.9) | 1.8 (1.2 to 2.6) | 1.6 (1.0 to 2.3) | <0.001 |
Acute kidney injury (%) | 36.1 | 17.7 | 27.4 | 44.1 | 56.4 | <0.001 |