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Table 2 Routine coagulation tests, clotting factor levels, hemoglobin, hematocrit, white blood count and CRP

From: Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study

Parameter

Normal range

Day 1

Day 2

Day 3

Discharge

Platelets (g/l)

140 to 380

191 ± 117

198 ± 135

196 ± 135

364 ± 201*

INR

0.9 to 1.15

1.18 ± 0.16

1.16 ± 0.18

1.12 ± 0.15

1.09 ± 0.14

aPTT (seconds)

25 to 36

48.1 ± 11.4

48.8 ± 13.0

44.7 ± 11.2

39.8 ± 11.6*

Fibrinogen (g/l)

1.3 to 3.6

6.2 ± 2.7

5.8 ± 1.6

5.5 ± 1.6

6.0 ± 4.4

Factor II (%)

81 to 134

61 ± 22

64 ± 25

69 ± 23

76 ± 28*

Factor V (%)

78 to 153

103 ± 45

110 ± 45

114 ± 43*

116 ± 33*

Factor VII (%)

70 to 139

66 ± 29

71 ± 29

88 ± 30*

79 ± 29

Factor X (%)

68 to 145

79 ± 29

81 ± 30

90 ± 22

84 ± 21

Hemoglobin (g/l)

121 to 154

100.4 ± 14.3

98.8 ± 14.7

98.9 ± 11.6

102.2 ± 12.2

Hematocrit (%)

0.36 to 0.44

29.1 ± 4.4

29.1 ± 4.8

29.2 ± 3.8

30.4 ± 3.7

WBC (g/l)

3.5 to 10.5

16.1 ± 7.5

17.4 ± 7.3

17.0 ± 6.4

16.6 ± 6.9

CRP (mg/l)

<5

201 ± 87

202 ± 83

176 ± 94

113 ± 76*

Creatinine (μmol/l)

59 to 104

172 ± 120

159 ± 113

171 ± 115

151 ± 126

Bilirubin (μmol/l)

3 to 26

33.3 ± 34.3

37.0 ± 40.5

40.0 ± 46.2

32.8 ± 43.9

  1. Values are expressed as Mean ± SD. *P < 0.05, versus baseline. aPTT, activated partial thromboplastin time; CRP, C-reactive protein; INR, International Normalized Ratio; WBC, white blood count.