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Table 5 Variables associated with post-thoracotomy acute lung injury

From: Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery

Characteristic

Unadjusted analysis

Adjusted analysis

 

Odds ratio (95% confidence interval)

P value

Odds ratio (95% confidence interval)

P value

Age, per 10-year increase

1.09 (0.80 to 1.89)

0.382

-

-

Chronic alcohol consumption

1.76 (1.11 to 5.2)

0.013

1.93 (1.14 to 5.71)

0.001

FEV1 < 60%

1.12 (0.78 to 2.05)

0.254

-

-

ASA class 3/4

1.21 (0.72 to 2.21)

0.214

-

-

ACE inhibitor therapy

0.85 (0.55 to 2.12)

0.315

-

-

Statin therapy

0.81 (0.45 to 2.97)

0.198

-

-

Chemo-radiotherapy

1.52 (1.09 to 3.83)

0.021

1.40 (0.91 to 2.98)

0.203

Advanced TNM stages (III to IV)

1.63 (1.09 to 3.01)

0.018

1.45 (0.87 to 2.84)

0.234

Thoracic epidural anesthesia

0.92 (0.78 to 1.92)

0.563

-

-

Duration of surgery

1.37 (0.78 to 2.67)

0.312

-

-

Red blood cell transfusion

1.09 (0.23 to 7.24)

0.789

-

-

Pneumonectomy

2.41 (1.29 to 8.12)

0.005

2.52 (1.34 to 7.71)

< 0.001

Fluid infused, per 1 ml/kg/hour increase

1.33 (1.02 to 5.08)

0.032

1.42 (1.09 to 4.32)

0.011

  1. ACE, angiotensin-converting enzyme; ASA, American Society of Anesthesiologists; FEV1, forced expiratory volume in 1 second; TNM, Tumor, Node, Metastasis.