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Figure 2 | Critical Care

Figure 2

From: Crystalloids versus colloids for goal-directed fluid therapy in major surgery

Figure 2

Regional blood flow parameters. (a) Changes in superior mesenteric artery flow index (mean ± SD) before (baseline) and during the different fluid treatment strategies. (b) Changes in hepatic artery flow index (mean ± SD) before (baseline) and during the different fluid treatment strategies. (c) Changes in carotid artery flow index (mean ± SD) before (baseline) and during the different fluid treatment strategies. The restricted Ringer lactate fluid therapy (R-RL) group received 3 mL/kg per hour of lactated Ringer solution throughout the entire experiment. The goal-directed Ringer lactate fluid therapy (GD-RL) group received 3 mL/kg per hour of lactated Ringer solution plus 250 mL of lactated Ringer solution if mixed venous oxygen saturation (SvO2) was less than 60%. The goal-directed colloid fluid therapy (GD-C) group received 3 mL/kg per hour of lactated Ringer solution plus 250 mL of hydroxyethyl starch (130/0.4) if SvO2 was less than 60%. Significant differences (P < 0.05) for area under the curve: #R-RL versus GD-RL, †R-RL versus GD-C, $GD-RL versus GD-C. Significant differences (P < 0.05) for analysis of variance for repeated measurements (Tukey post hoc test): *R-RL versus GD-RL, ≠R-RL versus GD-C, §GD-RL versus GD-C. SD, standard deviation.

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