Table 2 Comparison between Risk-Injury–Failure–Loss–Endstage renal disease and Acute Kidney Injury Network classifications

Risk, Injury, and Failure

Stages 1, 2 and 3

Loss and Endstage renal disease describe renal outcome after acute kidney injury episode

Not used

Uses change in creatinine or glomerular filtration rate, in addition to urine output criteria

Uses change in creatinine, in addition to urine output criteria

Risk: increased creatinine × 1.5 or glomerular filtration rate decrease >25%

Stage 1: increased creatinine × 1.5 or ≥ 0.3 mg/dl

Stage not specified for patients starting renal replacement therapy

Patients starting renal replacement therapy are classified as Stage 3, regardless of serum creatinine or urine output

Proposed timeframe of 1 week specified for making diagnosis of acute kidney injury

Acute kidney injury diagnosis is based on a change between two creatinine values within a 48-hour period^a

Not specified

Diagnostic criteria to be used only "after an optimal state of hydration has been achieved"