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Table 1 Acute kidney injury mortality (adults) and prevalence (pediatric) by different baseline creatinine values

From: Clinical review: RIFLE and AKIN – time for reappraisal

Method for estimating baseline creatinine

No acute kidney injury

Risk (%)

Injury (%)

Failure (%)

Crude mortality by RIFLE class (adults)

    

   Hospital admission

12.4

21.7

34.5

40.6

   ICU admission

12.7

21.7

31.2

38.4

   Lower of hospital or ICU admission

10.4

16.0

36.0

41.5

   Estimate from MDRD formula

5.7

12.7

25.2

34.9

   Lower of hospital or ICU admission or MDRD estimate

7.2

12.9

24.3

35.7

   Nadir creatinine (first week)

9.7

13.1

25.9

30.1

   Nadir creatinine (whole admission)

8.9

11.0

22.1

28.7

Acute kidney injury prevalence by pediatric RIFLE class (pediatric ICU)

    

   Estimated creatinine clearance of 120 ml/min/1.73 m2

36.5

17.1

24.4

22.0

   Estimated creatinine clearance of 100 ml/min/1.73 m2

17.1

14.6

36.6

31.7

   ICU admission

87.9

7.3

2.4

2.4

   Normal value for age and gender (minimum)

12.2

12.2

39.0

36.6

   Normal value for age and gender (maximum)

46.3

14.6

17.1

22.0

  1. Adapted from E Hoste (personal communication, with permission) and [18]. ICU, intensive care unit; MDRD, Modification of Diet in Renal Disease.