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Figure 3 | Critical Care

Figure 3

From: Resuscitation of haemorrhagic shock with normal saline vs. lactated Ringer's: effects on oxygenation, extravascular lung water and haemodynamics

Figure 3

Haemodynamic data during resuscitation. Boxplots for the means of the values at the time the difference in mean arterial pressure (MAP) between the two groups first became significant. (a) Significant differences in MAP, cardiac output (CO) and systemic vascular resistance (SVR). There were no differences in baseline values immediately prior to resuscitation between the groups. During the resuscitation stage MAP was lower in the normal saline (NS) group (NS 56.9 ± 1.6 mmHg vs. lactated Ringer's solution (LR) 64.0 ± 2.0 mmHg; p = 0.01) despite this group having higher COs (NS 5.2 ± 0.3 l/minute vs. LR 4.4 ± 0.2 l/minute; p = 0.016). This was due to a significant difference in SVR (NS 923 ± 51.4 dyne × sec/m3vs. 1177.6 ± 34.6 dyne × sec/m3; p < 0.001). (b) There were no differences in the preload metric global end-diastolic volume (GEDV) or in stroke volume (SV). The differences in CO seen in (a) were due to a significant increased heart rate (HR) in the NS group (NS 114.9 ± 6.5 beats/minute vs. LR 93.6 ± 3.6 beats/minute; p = 0.012).

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