Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage in an isolated renal perfusion model

Table 1 Haemodynamic variables during isolated renal perfusion

	Time (hours)	0	2	4	6
Blood flow (ml/g organ weight)
	HES 200/0.5	0.87 ± 0.15	0.92 ± 0.2	0.9 ± 0.24	0.98 ± 0.19
	HES 130/0.42	0.86 ± 0.12	0.87 ± 0.09	0.86 ± 0.08	0.96 ± 0.07
	RL	0.83 ± 0.18	0.94 ± 0.07	1.03 ± 0.19	0.98 ± 0.19
MAP (mmHg)
	HES 200/0.5	69 ± 6	74 ± 6	79 ± 8	78 ± 10
	HES 130/0.42	72 ± 9	77 ± 12	76 ± 9	81 ± 7
	RL	77 ± 10^c	69 ± 7^a	73 ± 11	77 ± 9

Values are mean ± standard deviation. There were no statistical differences between groups.
HES = hydroxyethyl starch; MAP = mean arterial pressure; RL = Ringer's lactate.

ISSN: 1364-8535