Table 2 Clinical outcomes according to treatment group
| Â | Control group (n = 27) | Decremental PEEP titration group (n = 30) | p value |
|---|---|---|---|
Responder (%) | 44.4 | 70 | 0.046 |
Clinical outcomes | Â | Â | Â |
   Duration of mechanical ventilation, days | 15.2 ± 3.2 | 19.8 ± 0.5 | 0.380 |
   Intensive care unit stay, days | 21.4 ± 5.3 | 25.1 ± 5.6 | 0.643 |
   Duration of paralysing agent, days | 9.0 ± 2.3 | 11.8 ± 2.0 | 0.358 |
   Duration of sedative agents, days | 14.2 ± 2.4 | 18.7 ± 3.4 | 0.303 |
   Weaning trial within seven days | 8 | 6 |  |
   Tracheostomy | 5 | 8 |  |
   Reintubation | 5 | 2 |  |
   Barotrauma | 3 | 3 |  |
   Ventilator-associated pneumonia | 5 | 5 |  |
Mortality, number (%) | Â | Â | Â |
   Mortality at 28 days | 9 (33.3) | 12 (40) | 0.784 |
   Death in the intensive care unit | 13 (48.1) | 14 (46.7) | 1.000 |
   Mortality at 60 days | 15 (55.6) | 14 (46.7) | 0.599 |
Cause of in-hospital death, number (%) | Â | Â | Â |
   Progressive respiratory failure | 8 (53.3) | 8 (57.1) |  |
   Refractory septic shock | 4 (26.7) | 2 (14.3) |  |
   Hepatic failure | 3 (20) | 2 (14.3) |  |
   Myocardial infarction |  | 2 (14.3) |  |
Rescue therapy (%) | Â | Â | Â |
   Prone position | 44.4 | 50.0 | 0.792 |
   Nitric oxide inhalation | 48.1 | 53.3 | 0.793 |