Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrome

Table 1 Baseline characteristics of the patients at enrollment

	Control group (n = 27)	Decremental PEEP titration group (n = 30)
Age (years)	62.0 ± 2.2	55.0 ± 3.7
Percentage of women	37	40
APACHE II score	20.0 ± 1.4	22.0 ± 1.1
Lung injury score	2.5 ± 0.1	2.8 ± 0.2
Tidal volume (ml/kg of predicted body weight)	8.0 ± 1.4	7.9 ± 1.9
Respiratory rate (breaths/minute)	22.0 ± 3.0	22.2 ± 3.2
Peak airway pressure (cmH₂O)	25.9 ± 5.9	27.8 ± 5.5
Positive end-expiratory pressure (cmH₂O)	7.0 ± 3.7	8.4 ± 3.1
Dynamic compliance (Cdyn, ml/cmH₂O)	25.7 ± 8.1	24.3 ± 7.6
PF ratio (PaO₂:FiO₂)	110.8 ± 6.3	115.0 ± 8.5
Co-morbidities, n
Haematological malignancy	3	7
Solid organ malignancy	6	4
Chronic liver disease	5	3
Connective tissue disease	2	1
Others^a	3	3
Cause of lung injury (ARDSp:ARDSexp)	18:9	20:10
Pneumonia	15	17
Sepsis	7	7
Massive transfusion	2	1
Pulmonary alveolar haemorrhage	1	1
Others^b	2	4

Data was presented as mean ± standard error of the mean. ^a including complicated diabetes mellitus (n = 4), Crohn's disease (n = 1) and AIDS (n = 1). ^b including leptospirosis (n = 3), near-drowning (n = 1), contusion (n = 1) and scrub typhus (n = 1). APACHE = acute physiology and chronic health evaluation; ARDSp = pulmonary ARDS; ARDSexp = extrapulmonary ARDS; FiO₂ = inspired fracture of oxygen; PaO₂ = partial arterial pressure of oxygen; PEEP = positive end-expiratory pressure.

ISSN: 1364-8535