| Control group (n = 27) | Decremental PEEP titration group (n = 30) |
---|---|---|
Age (years) | 62.0 ± 2.2 | 55.0 ± 3.7 |
Percentage of women | 37 | 40 |
APACHE II score | 20.0 ± 1.4 | 22.0 ± 1.1 |
Lung injury score | 2.5 ± 0.1 | 2.8 ± 0.2 |
Tidal volume (ml/kg of predicted body weight) | 8.0 ± 1.4 | 7.9 ± 1.9 |
Respiratory rate (breaths/minute) | 22.0 ± 3.0 | 22.2 ± 3.2 |
Peak airway pressure (cmH2O) | 25.9 ± 5.9 | 27.8 ± 5.5 |
Positive end-expiratory pressure (cmH2O) | 7.0 ± 3.7 | 8.4 ± 3.1 |
Dynamic compliance (Cdyn, ml/cmH2O) | 25.7 ± 8.1 | 24.3 ± 7.6 |
PF ratio (PaO2:FiO2) | 110.8 ± 6.3 | 115.0 ± 8.5 |
Co-morbidities, n | Â | Â |
   Haematological malignancy | 3 | 7 |
   Solid organ malignancy | 6 | 4 |
   Chronic liver disease | 5 | 3 |
   Connective tissue disease | 2 | 1 |
   Othersa | 3 | 3 |
Cause of lung injury (ARDSp:ARDSexp) | 18:9 | 20:10 |
   Pneumonia | 15 | 17 |
   Sepsis | 7 | 7 |
   Massive transfusion | 2 | 1 |
   Pulmonary alveolar haemorrhage | 1 | 1 |
   Othersb | 2 | 4 |