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Table 1

From: Endotoxin-induced pulmonary hyporesponsiveness to inhaled nitric oxide is improved by nitric oxide synthase 2 inhibition

   ? PAP (mmHg)  
  0.4ppm NO 4ppm NO 40ppm NO
Control -1.94± 0.63 -4.01± 1.16 -5.28± 0.86
LPS+3mg/kg AG   -2.32± 1.37*   -4.98± 1.69*   -6.16± 2.55*
LPS+10mg/kg AG   -1.98± 1.12*   -4.02± 2.16*   -6.22± 1.65*
LPS+30mg/kg AG   -1.32± 0.79# -  3.37± 1.80*     -5.53± 1.27*#
LPS+0.01mg/kg SMT   -0.44± 0.33# -  1.60± 1.23# -2.64± 1.71
LPS+0.1mg/kg SMT   -0.24± 0.27# -  1.28± 0.97#   -1.96± 1.51#
LPS+1mg/kg SMT   -1.75± 1.32*   -3.70± 0.79*   -5.75± 2.47*
LPS+10mg/kg SMT   -0.30± 0.42# -  0.50± 0.51#   -1.77± 0.40#
LPS   -0.12± 0.15#   -0.64± 0.68*   -0.98± 0.65#
  1. *P<0.05 vs treatment with LPS alone; # P<0.05 vs control; data are mean ± SEM (Scheffe-test).