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Table 2 Logistic regression parameters. The outcome of logistic regression is shown for a model where intensive care unit (ICU) stay more than three days is the dependent variable (primary outcome). The covariates entered into the model were IL-18 9545 genotype, age, gender, duration of bypass, pre-operative ejection fraction and whether the patient had diabetes or renal dysfunction. Renal dysfunction was defined as baseline creatinine more than 200 μmol/L

From: Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery

Covariate

Relative risk

of ICU stay > three days

95% confidence interval

p value

IL-18 9545 TT versus TG/GG genotype

3.01

1.28 to 7.10

0.012

Age (per year)

1.01

0.98 to 1.04

0.608

Gender (female)

0.95

0.40 to 2.27

0.905

Duration of bypass (per hour)

2.09

1.49 to 2.93

0.000

Ejection fraction (per %)

0.97

0.95 to 1.0

0.026

Diabetes

1.10

0.50 to 2.43

0.806

Renal dysfunction

1.77

0.36 to 8.63

0.482