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Table 1 Baseline characteristics by IL-18 9545 genotype

From: Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery

 

9545 TT

9545 GT

9545 GG

Total

p value

Number (%)

383 (58)

225 (34)

50 (8)

658

 

Age (years)

65 ± 1

66 ± 1

66 ± 1

66 ± 1

0.655

Male sex (%)

77

77

70

76

0.544

Body mass index (kg/m2)

28 ± 1

28 ± 1

26 ± 1

28 ± 1

0.022

Ejection fraction (%)

49.2 ± 0.7

48.8 ± 0.9

51.3 ± 2.1

49.3 ± 0.5

0.529

Renal dysfunction (%) (Creatinine > 200 μmol/L)

3.6

2.2

0.0

2.9

0.266

Diabetes (Types I & II) (%)

29

28

27

28

0.969

Smoking (%)

32

41

36

32

0.129

Anti-hypertensive use (%)

65

61

58

62

0.495

Angiotensin-converting enzyme II inhibitor use (%)

48

54

50

52

0.447

Beta-blocker use (%)

58

60

56

59

0.745

Aspirin use (%)

59

59

60

59

0.992

Duration of surgery (hours)

4.4 ± 0.1

4.5 ± 0.1

4.4 ± 0.1

4.5 ± 0.1

0.728

Duration of bypass (hours)

1.8 ± 0.1

1.9 ± 0.1

1.8 ± 0.1

1.8 ± 0.1

0.544

Cross clamp time (hours)

1.3 ± 0.1

1.4 ± 0.1

1.4 ± 0.1

1.4 ± 0.1

0.143

  1. Continuous variables are reported as mean ± standard error of the mean.