Figure 3
From: Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery
Prolonged intensive care unit (ICU) stay and low Systemic Vascular Resistance Index (SVRI) after cardiopulmonary bypass (CPB) by interleukin (IL)-18 9545 T/G genotype in Caucasian patients who underwent on-pump CPB surgery. Percentage of patients having prolonged ICU stay (greater than 72 hours) are indicated on the first Y-axis and percentage of patients having low SVRI after CPB surgery are indicated on the second Y-axis. IL-18 9545 T/G genotypes are indicated on the X-axis. Patients homozygous for the T allele of the IL-18 9545 T/G SNP had significantly greater occurrence of prolonged ICU stay and significantly increased occurrence of low SVRI after CPB compared with all others (GT and GG genotypes).