Table 2 Clinical and biochemical data of patients with alcoholic hepatitis and patients with resistant pruritus before and after the seven-hour sessions of albumin dialysis
Patients with alcoholic hepatitis n dialysis = 23 | Patients with resistant pruritus n dialysis = 8 | |||||
|---|---|---|---|---|---|---|
Before | After | p | Before | After | p | |
Encephalopathy (score) | 0.36 ± 0.11 | 0.16 ± 0.09 | 0.02 | 0 | 0 | n.s. |
NCT (minute) | 3.28 ± 0.43* | 2.8 ± 0.31 | n.s. | 1.17 ± 0.11 | 1.03 ± 0.08 | n.s. |
Bilirubin (mg/dl) | 20.6 ± 1.5 | 16.3 ± 1.5 | 0.001 | 1.01 ± 0.1 | 1.2 ± 0.1 | n.s. |
Albumin (g/L) | 24.2 ± 0.6 | 25.5 ± 0.7 | 0.03 | 37.4 ± 0.7 | 38.2 ± 1.4 | n.s. |
Prothrombin index (%) | 34.4 ± 1.9 | 30.3 ± 2.2 | 0.03 | 92.0 ± 4.8 | 84.1 ± 5.9 | n.s. |
Creatinine | 1.3 ± 0.3 | 0.7 ± 0.1 | 0.008 | 0.85 ± 0.05 | 0.78 ± 0.12 | n.s. |
Serum Na | 134 ± 1.0 | 138 ± 0.6 | 0.0003 | 138 ± 0.4 | 138 ± 0.4 | n.s. |
Serum K | 3.7 ± 0.1 | 4.0 ± 0.1 | 0.05 | 4.1 ± 0.1 | 4.5 ± 0.2 | 0.04 |
Haemoglobin (g/L) | 10.0 ± 0.4 | 9.4 ± 0.4 | 0.002 | 11.8 ± 0.4 | 11.4 ± 0.6 | n.s. |
Leucocytes (cell/×109) | 11.9 ± 1.4 | 11.1 ± 1.4 | 0.06 | 8.2 ± 1.2 | 7.3 ± 0.6 | n.s. |
Platelets (cell/×109) | 78.6 ± 7.0 | 56.0 ± 6.0 | 0.0000 | 234 ± 19 | 187 ± 19 | 0.01 |
Total amino acids (μM/L) | 2491 ± 152 | 2229 ± 114 | 0.01 | 2080 ± 159 | 2354 ± 158 | n.s. |
Branched AA (μM/L) | 243 ± 18 | 233 ± 12 | n.s. | 399 ± 44 | 443 ± 47 | n.s. |
Phenolic aromatic AA (μM/L) | 193 ± 17 | 165 ± 10 | 0.04 | 123 ± 10 | 145 ± 11 | 0.05 |
Fischer index | 1.32 ± 0.08 | 1.47 ± 0.05 | 0.01 | 3.20 ± 0.16 | 3.08 ± 0.24 | n.s. |
Tryptophan (μM/L) | 28.4 ± 1.9 | 26.0 ± 1.8 | n.s. | 45.0 ± 2.6 | 42.9 ± 4.8 | n.s. |
Ammonium (μM/L) | 46.2 ± 6.6 | 41.1 ± 5.5 | n.s. | 22.2 ± 4.1 | 21.5 ± 3.2 | n.s. |