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Table 1 Baseline characteristics of the studied sample of long-stay patients

From: Benefits of intensive insulin therapy on neuromuscular complications in routine daily critical care practice: a retrospective study

 

Total population n = 620

Surgical intensive care unit n = 476

Medical intensive care unit n = 144

 

Before IIT n = 168

After IIT n = 452

p-value

Before IIT n = 62

After IIT n = 414

p-value

Before IIT n = 106

After IIT n = 38

p-value

Male/female sex, n (%)

105/168 (62.5)

305/452 (67.5)

0.2

41/62 (66.1)

285/414 (68.8)

0.7

64/106 (60.4)

20/38 (52.6)

0.4

Age, years (mean ± SD)

61 ± 15

62 ± 14

0.4

64 ± 13

63 ± 14

0.6

60 ± 15

61 ± 17

0.9

ICU type/MICU total n (%)

106/168 (63.1)

38/452 (8.4)

< 0.0001

      

Diagnostic group, total n (%) of the category

  

< 0.0001

  

0.1

   

Abdominal/gastro- intestinal/liver

19/71 (26.8)

52/71 (73.2)

 

6/55 (10.9)

49/55 (89.1)

 

13/16 (81.3)

3/16 (18.7)

 

Cardiovascular

24/171 (14.0)

147/171 (86.0)

 

21/167 (12.6)

146/167 (87.4)

 

3/4 (75.0)

1/4 (25.0)

 

Cerebral/neurological

6/60 (10.0)

54/60 (90.0)

 

2/52 (3.8)

50/52 (96.2)

 

4/8 (50.0)

4/8(50.0)

 

Haematological/oncol ogy/transplant

3/31 (9.7)

28/31 (90.3)

 

2/29 (6.9)

27/29 (93.1)

 

1/2 (50.0)

1/2 (50.0)

 

Other

32/73 (43.8)

41/73 (56.2)

 

10/43 (23.3)

33/43 (76.7)

 

22/30 (73.3)

8/30 (26.7)

 

Polytrauma

6/37 (16.2)

31/37 (83.8)

 

6/37 (16.2)

31/37 (83.8)

 

0/0

0/0

 

Respiratory/thoracic

61/136 (44.9)

75/136 (55.1)

 

8/64 (12.5)

56/64 (87.5)

 

53/72 (73.6)

19/72 (26.4)

 

History of diabetes, total n (%)

  

0.2

  

0.9

  

0.07

Insulin treated

11/151 (7.3)

26/420 (6.2)

 

3/55 (5.5)

23/384 (6.0)

 

8/96(8.3)

3/36 (8.3)

 

Oral antidiabetic treatment and/or diet

16/151 (10.6)

26/420 (6.2)

 

3/55 (5.5)

26/384 (6.8)

 

13/96 (13.5)

0/36 (0)

 

Baseline APACHE II, (mean ± SD)

19.0 ± 8.3

16.2 ± 7.1

< 0.0001

14.6 ± 6.7

15.7 ± 6.9

0.3

21.7 ± 8.1

21.5 ± 7.5

0.9

On admission blood glucose, mg/dl median (IQR)

157 (126 to 202)

134 (107 to 172)

< 0.0001

163 (126 to 199)

135 (109 to 173)

0.007

151 (126 to 202)

124 (96 to 156)

0.008

On admission mechanical ventilation, total n (%)

133/140 (95.0)

402/413 (97.3)

0.2

55/55 (100)

375/381 (98.4)

0.3

78/85 (91.8)

27/32 (84.4)

0.2

  1. APACHE = acute physiology and health evaluation; IIT = intensive insulin therapy; IQR = interquartile range; MICU = medical intensive car unit; n = number; SD = standard deviation.