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Table 1 Demographic and clinical characteristics of 167 patients following aneurysmal subarachnoid haemorrhage

From: Cerebral microdialysis for detection of bacterial meningitis in aneurysmal subarachnoid hemorrhage patients: a cohort study

 

All patients

(n = 167)

Meningitis

(n = 20)

Controls

(n = 147)

p

Age

50.8 ± 12.6

53.5 ± 9.7

50.4 ± 13.0

p = 0.292

Gender: male/female

46/121

5/15

41/106

p = 0.802

Admission WFNS grade

2.7 ± 1.6

3.6 ± 1.3

2.6 ± 1.6

p = 0.009

   0

3 (2%)

0 (0%)

3 (2%)

 

   I

58 (35%)

2 (10%)

56 (38%)

 

   II

21 (13%)

3 (15%)

18 (12%)

 

   III

18 (11%)

2 (10%)

16 (11%)

 

   IV

38 (23%)

8 (40%)

30 (20%)

 

   V

29 (17%)

5 (25%)

24 (16%)

 

Clinical group

   

p = 0.867

   Asymptomatic

66 (40%)

8 (40%)

58 (40%)

 

   AFND

58 (35%)

6 (30%)

52 (35%)

 

   DIND

43 (26%)

6 (30%)

37 (25%)

 

Time SAH – surgery (hours)

45.0 ± 74.4

61.0 ± 133.3

42.8 ± 62.3

p = 0.519

Fisher-score

3.0 ± 1.0

3.5 ± 0.6

3.0 ± 1.0

p = 0.059

Duration of microdialysis (hrs)

165.4 ± 83.8

185.2 ± 96.8

162.8 ± 81.9

p = 0.252

Presence of CSF drainage

77 (46%)

18 (90%)

59 (40%)

p = 0.001

ICU stay (days)

15.1 ± 9.3

20.6 ± 6.9

14.3 ± 9.4

p = 0.003

GOS at 6 months after SAH

3.8 ± 1.4

4.0 ± 1.2

3.8 ± 1.4

p = 0.889

Mortality rate at 6 months

20 (13%)

1 (6%)

19 (14%)

p = 0.322

  1. P values are given for comparison of patients developing meningitis and controls (calculated by Mann-Whitney-U-Test or, for dichotomous data, by chi-squared test, exact versions).
  2. AFND = acute focal neurological deficit; CSF = cerebrospinal fluid; DIND = delayed ischaemic neurological deficit; GOS = Glasgow outcome scale; ICU = intensive care unit; SAH = subarachnoid haemorrhage; WFNS = World Federation of Neurological Surgeons.