| Control | Low VT | High VT | ||
---|---|---|---|---|---|
 |  | NaCl | NaHCO3 | NaCl | NaHCO3 |
PH | 7.34 (0.05) | 7.22 (0.04)* | 7.42 (0.05) | 7.11 (0.07)‡ | 7.37 (0.08) |
PaCO2 (mmHg) | 39.3 (31.6 to 51.3) | 35.7 (31.1 to 39.5) | 41.2 (35.3 to 43.6) | 40.8 (37.0 to 55.6) | 44.3 (36.1 to 51.7) |
PaO2 (mmHg) | Â | 193 (36) | 168 (48) | 173 (51) | 161 (50) |
HCO3- (mmol/l) | 21.1 (17.9 to 24.1) | 14.4 (12.9 to 15.2) | 25.2 (23.6 to 25.9) | 13.5 (12.1 to 14.7) | 24.5 (22.7 to 25.4) |
BE | -3.9 (-6.2 to -2.5) | -12.3 (-13.6 to -11.8) | 0.15 (-1.1 to 2.2) | -15.9 (-16.7 to -14.8) | -0.7 (-2.4 to -0.1) |