| Control | Low VT | High VT | ||
---|---|---|---|---|---|
 |  | NaCl | NaHCO3 | NaCl | NaHCO3 |
pH | 7.42 (0.04) | 7.17 (0.07)‡ | 7.41 (0.07) | 7.23 (0.06)‡ | 7.49 (0.02) |
PaCO2 (mmHg) | 34.4 (32.2 to 38.3) | 50.1 (36.7 to 59.6) | 45.0 (38.6 to 50.0) | 33.7 (32.1 to 34.0) | 31.0 (27.6 to 34.4) |
PaO2 (mmHg) | Â | 133 (15) | 148 (28) | 186 (45) | 223 (20) |
HCO3- (mmol/l) | 21.4 (21.1 to 24.1) | 16.6 (15.2 to 18.9) | 28.0 (26.1 to 30.0) | 14.6 (13.3 to 15.6) | 24.9 (21.3 to 25.5) |
BE | -1.3 (-2.3 to -0.5) | -11.7 (-12.5 to -10.2) | 4.1 (1.3 to 6.0) | -12.8 (-13.4 to -10.1) | 2.3 (-0.4 to 2.9) |