Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review

Table 6 Performance for combined models.

APACHE II	Given by	AUC	Brier	H/C statistics	Mortality
APACHE II	Ho (2007) [4]	0.859	0.09	C = 10 p = 0.189	Hospital
APACHE II + Total Max SOFA	Ho (2007) [4]	0.875	0.086	C = 10.1 p = 0.261	Hospital
APACHE II + Delta SOFA	Ho (2007) [4]	0.874	0.086	C = 7.5 p = 0.485	Hospital
APACHE II + Admission SOFA	Ho (2007) [4]	0.861	0.09	C = 9.3 p = 0.318	Hospital
SAPS II	Given by	AUC	Brier	H/C statistics	Mortality
SAPS II	Rivera-Fernández et al (2007) [5]	0.8			ICU
SAPS II + Diagnosis	Rivera-Fernández et al (2007) [5]	0.84			ICU
SAPS II + Diagnosis + Events	Rivera-Fernández et al (2007) [5]	0.91			ICU
SAPS II + Mean SOFA + Max SOFA + Events	Rivera-Fernández et al (2007) [5]	0.93			ICU
SAPS II + Mean SOFA+ Max SOFA + Events + Diagnosis	Rivera-Fernández et al (2007) [5]	0.95		H: 12.02 p > 0.05	ICU
Other covariates	Given by	AUC	Brier	H/C statistics	Mortality
Min SOFA + Max SOFA+ SOFA trend over 5 days + Age	Cabré et al (2005) [6]	0.807			Hospital
Max SOFA > 13 + Min SOFA > 10 + Positive SOFA trend + Age > 60	Cabré et al (2005) [6]	0.750			Hospital
Max SOFA > 10 + Min SOFA > 10 + Positive SOFA trend + Age > 60	Cabré et al (2005) [6]	0.758			Hospital
Total Max SOFA	Kajdacsy-Balla Amaral et al (2005) [7]	0.841			ICU
Total Max SOFA + Infection	Kajdacsy-Balla Amaral et al (2005) [7]	0.845			ICU
Total Max SOFA + Infection + Age	Kajdacsy-Balla Amaral et al (2005) [7]	0.853		C: p = 0.37	ICU
				H: p = 0.73

APACHE = Acute Physiology and Chronic Health Evaluation, AUC = Area Under the Receiver Operating Characteristic Curve, ICU = Intensive care unit, max = maximum, min = minimum, SAPS = Simplified Acute Physiology Score, SOFA = Sequential Organ Failure Assessment.

ISSN: 1364-8535