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Table 6 Performance for combined models.

From: Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review

APACHE II Given by AUC Brier H/C statistics Mortality
APACHE II Ho (2007) [4] 0.859 0.09 C = 10 p = 0.189 Hospital
APACHE II + Total Max SOFA Ho (2007) [4] 0.875 0.086 C = 10.1 p = 0.261 Hospital
APACHE II + Delta SOFA Ho (2007) [4] 0.874 0.086 C = 7.5 p = 0.485 Hospital
APACHE II + Admission SOFA Ho (2007) [4] 0.861 0.09 C = 9.3 p = 0.318 Hospital
SAPS II Given by AUC Brier H/C statistics Mortality
SAPS II Rivera-Fernández et al (2007) [5] 0.8    ICU
SAPS II + Diagnosis Rivera-Fernández et al (2007) [5] 0.84    ICU
SAPS II + Diagnosis + Events Rivera-Fernández et al (2007) [5] 0.91    ICU
SAPS II + Mean SOFA + Max SOFA + Events Rivera-Fernández et al (2007) [5] 0.93    ICU
SAPS II + Mean SOFA+ Max SOFA + Events + Diagnosis Rivera-Fernández et al (2007) [5] 0.95   H: 12.02 p > 0.05 ICU
Other covariates Given by AUC Brier H/C statistics Mortality
Min SOFA + Max SOFA+ SOFA trend over 5 days + Age Cabré et al (2005) [6] 0.807    Hospital
Max SOFA > 13 + Min SOFA > 10 + Positive SOFA trend + Age > 60 Cabré et al (2005) [6] 0.750    Hospital
Max SOFA > 10 + Min SOFA > 10 + Positive SOFA trend + Age > 60 Cabré et al (2005) [6] 0.758    Hospital
Total Max SOFA Kajdacsy-Balla Amaral et al (2005) [7] 0.841    ICU
Total Max SOFA + Infection Kajdacsy-Balla Amaral et al (2005) [7] 0.845    ICU
Total Max SOFA + Infection + Age Kajdacsy-Balla Amaral et al (2005) [7] 0.853   C: p = 0.37 ICU
     H: p = 0.73  
  1. APACHE = Acute Physiology and Chronic Health Evaluation, AUC = Area Under the Receiver Operating Characteristic Curve, ICU = Intensive care unit, max = maximum, min = minimum, SAPS = Simplified Acute Physiology Score, SOFA = Sequential Organ Failure Assessment.