Figure 5From: Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shockCD14+ monocytes of patients with septic shock (S) (n = 20) compared with healthy controls (C) (n = 20). Immunoblot analysis of protein expression and equal loading of total protein controlled by Poinceau red staining and densitometric quantification are shown. (a) Beta2-adrenergic receptors (β2-ARs) of membranes, (b) adenylate cyclase (AC) of cytosol, (c) α-subunits of stimulatory G protein (Gsα) of membranes, and (d) α-subunits of the inhibitory G protein (Giα) of membranes are shown. * P < 0.001 versus control. Con, control.Back to article page