Figure 4From: Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shockLipopolysaccharide (LPS)-induced tumor necrosis factor-alpha (TNF-α) expression in CD14+ monocytes of patients with septic shock and healthy controls. LPS-induced (100 ng/mL) TNF-α expression in CD14+ monocytes of patients with septic shock (n = 20) and healthy controls (n = 20) in the absence (Con) and presence of isoprenaline (Iso), forskolin (Forsk), or rolipram (Roli) (all 1 μmol/L). *P < 0.05 versus respective control. §P < 0.05 versus Iso in healthy volunteers group.Back to article page