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Table 1 Demographic and clinical characteristics of the 311 patients at the time of diagnosis of the first episode of severe sepsis. See definitions in the text and list of abbreviations for meaning

From: Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study

   Parameter 95% CI
  Median IQR  
Age (years) 68 54.9 to 74.5  
  No. %  
Sex (male) 208 66.9 61.3 to 72.1
McCabe score:    
   0 81 26 21.2 to 31.2
   1 131 42.1 36.5 to 47.8
   2 63 20.3 15.9 to 25.1
   3 36 11.6 8.2 to 15.7
Category:    
   Medical 179 57.6 51.9 to 63.1
   Urgent surgery 93 29.9 24.9 to 35.3
   Scheduled surgery 23 7.4 4.7 to 10.9
   Traumatological 16 5.1 3.0 to 8.2
Origin:    
   Medical and Surgical ward 167 53.7 48.0 to 59.0
   Emergency department 67 21.5 12.5 to 21.0
   Operating room 51 16.4 17.1 to 26.5
   Other 26 8.3 5.5 to 12.0
Comorbidities:    
   Chronic respiratory failure 46 14.8 11.0 to 19.2
   Immunodeficiency 41 13.2 9.6 to 17.5
   Risk of bleeding 31 10 6.9 to 13.8
   Chronic alcoholism 25 8 5.3 to 11.6
   Chronic renal failure 23 7.4 4.7 to 10.9
   IDDM 22 7.1 4.5 to 10.5
   Metastatic cancer 17 5.5 3.2 to 8.6
   Chronic heart failure 15 4.8 2.7 to 7.8
   Chronic liver failure 14 4.5 2.5 to 7.4
   AIDS 4 1.3 0.4 to 3.3
No. of comorbidities:    
   None 140 45 39.4 to 50.7
   One 114 36.7 31.3 to 42.3
   Two 46 14.8 11.0 to 19.2
   Three or more 11 3.5 1.8 to 6.2
Organ failure:    
   Respiratory 233 74.9 69.7 to 79.6
   Shock 180 57.9 52.1 to 63.4
   Cardiovascular 158 50.8 45.1 to 56.5
   Renal 124 39.9 34.4 to 45.6
   Haematological 69 22.2 17.7 to 27.2
   Liver 40 12.9 9.3 to 17.1
   Neurological 37 11.9 8.5 to 16.0
No. of organ failures:    
   One 68 21.9 17.4 to 26.9
   Two 86 27.7 22.8 to 32.0
   Three 81 26 21.3 to 31.3
   Four 39 12.5 9.1 to 16.7
   Five or more 37 11.9 6.6 to 16.0
  Median Mean (SD)  
APACHE II score (D1) 25 25.5 (± 7.1) 24.5 to 26.2
LODS score (D0) 6 6.3 (± 3.6) 5.9 to 6.7
SOFA score (D1) 10 9.6 (± 3.7) 9.2 to 10.0
  1. APACHE II, Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; D0: day 0; D1: day 1; IDDM, insulin-dependent diabetes mellitus; IQR: interquartile range; LODS, Logistic Organ Dysfunction System; SD, standard deviation; SOFA, Sepsis-related Organ Failure Assessment.