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Table 6 SMART: Hosmer-Lemeshow goodness-of-fit test results for prediction of shock and organ failure and survival in severe sepsis from baseline plus serial data

From: Prospectively validated predictions of shock and organ failure in individual septic surgical patients: the Systemic Mediator Associated Response Test

 

Day

Independent variable

1

2

3

4

5

6

7

14

21

28

Chest radiography score*

-

-

-

-

-

-

-

-

-

-

Mechanical ventilation

-

-

-

3.5003

11.159

3.5366

4.7716

16.473

14.65

3.8411

    

(NS)

(0.0836)

(0.1706)

(0.6878)

(0.0001)

(0.048)

(0.8712)

ARDS

-

50.182

5.1079

229.18

6.7868

7.4788

162.02

20.147

13.294

5.5629

  

(0.0001)

(NS)

(0.0001)

(0.079)

(0.2788)

(0.0001)

(0.0026)

(0.0099)

(0.5916)

DIC

-

6.061

2.513

2.1413

179.27

4.8029

2.4973

8.0683

245.38

-

  

(0.7338)

(0.4261)

(0.9764)

(0.0001)

(0.6840)

(NS)

(NS)

(0.0001)

 

Hepatobiliary failure

-

4969

42.872

11.154

19.672

25.623

40.83

23.322

3.1979

9.207

  

(0.0001)

(0.0001)

(0.1321)

(0.201)

(0.0003)

(0.0001)

(0.0015)

(0.959)

(0.3251)

Renal insufficiency

-

0.8232

3297.6

1.4857

20.514

2172

14.25

20.981

12.247

8.1239

  

(NS)

(0.0001)

(0.9604)

(0.0086)

(0.0001)

(0.0759)

(0.0072)

(0.0927)

(0.0044)

Shock

-

14.611

89.307

11.089

20.737

74.51

38.134

62.76

14.042

-

  

(0.0413)

(0.0001)

(0.1348)

(0.0020)

(0.0001)

(0.0001)

(0.0001)

(0.0001)

 

Survival status

-

10.315

15.226

8.8376

13.146

13.146

11.177

13.851

5.54

7.3106

  

(0.2436)

(0.0849)

(0.2645)

(0.0686)

(0.0686)

(0.2688)

(0.5835)

(0.5944)

(0.5835)

GCS score < 11

-

1064.3

105.34

729.5

5418

33.064

16.397

16.07

4.2473

0.8312

  

(0.0001)

(0.0001)

(0.0001)

(0.0001)

(0.0001)

(0.0217)

(0.0654)

(0.9355)

(NS)

  1. Values are Hosmer-Lemeshow goodness-of-fit test statistics (P values). *Chest radiography score = 0-4 quadrants pulmonary edema. Organ failure and shock definitions were from Fisher et al [18]. GCS Glascow Coma Scale; NS, not significant.