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Table 5 SMART: Hosmer-Lemeshow goodness-of-fit test results for prediction of shock and organ failure and survival in severe sepsis from baseline data only

From: Prospectively validated predictions of shock and organ failure in individual septic surgical patients: the Systemic Mediator Associated Response Test

  Day
Independent variable 1 2 3 4 5 6 7 14 21 28
Chest radiography score* -   - - - - - - - - -
ARDS 24.702 0.9667 100.87 61.879 35.996 11.435 102.25 18.64 4.524 3.3114
  (0.0009) (NS) (0.0001) (0.001) (0.0001) (0.2470) (0.0001) (0.0061) (0.807) (NS)
DIC 7.4046 4.581 4.0234 4.3578 13.231 9.4627 31.293 617.34 9.247 -
  (0.3880) (0.8692) (0.8550) (0.8235) (0.0667) (0.221) (0.0001) (0.0001) (NS)  
Hepatobiliary failure 14.349 5032 15.346 2.8502 22.643 18.508 16.223 242.39 24.656 7.3931
  (0.0453) (0.0001) (0.0318) (0.9434) (0.0121) (0.0177) (0.0232) (0.0001) (0.0009) (0.4949)
Renal insufficiency 67.172 200.8 22.777 18.597 26.06 131.14 37.378 12.759 25.071 15.32
  (0.0001) (0.0001) (0.0037) (0.0172) (0.0005) (0.0001) (0.0001) (NS) (0.0007) (0.0532)
Shock 12.115 10.962 10.233 20.961 0.0443 2.2016 22.485 119.08 15.938 0.0009
  (0.1461) (0.2783) (0.2491) (0.0073) (NS) (NS) (0.0075) (0.0001) (0.0433) (NS)
GCS score < 11 405.35 67.866 65.427 22.233 83.405 46.674 21.497 21.66 137.24 12.087
  (0.0001) (0.0001) (0.0001) (0.0001) (0.0001) (0.0001) (0.0059) (0.010) (0.0001) (0.0977)
  1. Values are Hosmer-Lemeshow goodness-of-fit test statistics (P values). *Chest radiography score = 0-4 quadrants pulmonary edema. Organ failure and shock definitions were from Fisher et al [18]. GCS Glascow Coma Scale; NS, not significant.