Table 2 Clinical definitions for organ failure and shock

Shock

Systolic blood pressure = 90 mmHg or mean

= 70 mmHg, or need for vasopressors

Renal

Serum creatine = 2.0 mg/dl, the need for dialysis, or

dysfunction

increase in serum creatine = 20 mg/dl above

pre-existing normal

Hepatic

Two or more of the following: serum bilirubin

dysfunction

= 25 mg/dl; alanine aminotransferase or aspartate

aminotransferase = 2 times normal; and prothrombin

time = 1.5 times normal

DIC

Two or more of the following: prothrombin or partial

thromboplastin time = 1.2 times normal; platelet count

= 100 000 mm⁵; and fibrin split products or D-dimer

> 0.5 mg/l

ARDS

Lung injury score = 7 [20]

Cerebral

Glasgow Coma Scale score < 11

dysfunction