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Table 2 Physiological effects and risks in the critically ill morbidly obese patient

From: Clinical review: Ventilatory strategies for obstetric, brain-injured and obese patients

Respiratory

Reduced lung volumes

 

Atelectasis and ventilation–perfusion mismatch

 

Increased work of breathing and oxygen consumption

 

Obstructive airways disease (mechanical and asthma)

 

Obstructive sleep apnea

 

Obesity hypoventilation syndrome

Cardiovascular

Coronary artery disease

 

Hypertension

 

Systolic and diastolic left ventricular dysfunction

 

Pulmonary arterial hypertension

 

Obesity supine death syndrome

Other

Diabetes mellitus

 

Increased risk of venous thromboembolism

 

Increase risk of gastric acid aspiration

 

Altered drug pharmacokinetics

 

Difficult venous access

 

Increased risk of renal failure

 

Increased risk of pressure ulcers