Table 1 Demographic, clinical and laboratory characteristics of patients
Characteristics | Total | Non-septic patients | Severe sepsis | Septic shock |
|---|---|---|---|---|
Number of patients | 43 | 14 | 12 | 17 |
Male | 25 (59%) | 6 (43%) | 5 (42%) | 14 (82%) |
Female | 18 (41%) | 8 (57%) | 7 (58%) | 3 (18%) |
Age (years, median (min – max) | 51 (21 to 73) | 59 (37 to 73) | 51 (43 to 69) | 51 (39 to 64) |
Reason for medical ICU admission | ||||
Pulmonary | 15 (35%) | 4 (29%) | 3 (25%) | 8 (47%) |
Abdominal | 10 (23%) | 2 (14%) | 4 (33%) | 4 (24%) |
Urogenital/retroperitoneal | 3 (7%) | 1(7%) | 2 (17%) | 0 (0%) |
Cardiac | 4 (9%) | 3 (21%) | 0 (0%) | 1 (6%) |
Cerebrovascular | 4 (9%) | 4 (29%) | 0 (0%) | 0 (0%) |
Bloodstream infections | 4 (9%) | 0 (0%) | 2 (17%) | 2 (12%) |
Miscellaneous | 3 (7%) | 0 (0%) | 1 (8%) | 2 (12%) |
Mean arterial pressure (mmHg) | 70 (40 to 96) | 67 (53 to 84) | 76 (67 to 91) | 72 (60 to 81) |
Heart rate (bpm) | 100 (50 to 145) | 102 (88 to 120) | 90 (78 to 110) | 106 (87 to 129) |
Noradrenaline (μg/kg/min) | 0.19 (0.0 to 1.96) | 0.025 (0.0 to 0.07) | 0.115 (0.02 to 0.18) | 0.57 (0.32 to 0.77) |
Mechanically ventilated, no. | 36 (84%) | 6 (43%) | 12 (100%) | 17 (100%) |
FiO2 (%) | 45 (26 to 100) | 40 (34.53) | 42 (35 to 62) | 50 (59 to 60) |
PaO2/FiO2 | 240 (68 to 640) | 269 (218 to 367) | 200 (130 to 257) | 190 (138 to 272) |
CRP (mg/L) | 129 (51 to 268) | 117 (5 to 194) | 172 (79 to 304) | 136 (54 to 282) |
Creatinine (mmol/L) | 251 (160 to 401) | 116 (54 to 302) | 354 (210 to 431) | 273 (188 to 427) |
Lactate (mmol/L) | 1.9 (1.2 to 2.9) | 1.3 (0.9 to 2.0) | 1.6 (1.0 to 2.1) | 2.9 (2.1 to 10.6) |
APACHE II score | 30 (6 to 48) | 26 (17 to 30) | 32 (25 to 35) | 32 (29 to 38) |
SOFA score | 16 (1 to 22) | 8 (4 to 11) | 17 (14 to 20) | 18 (16 to 20) |
Mortality | 25 (59%) | 4 (29%) | 8 (67%) | 13 (77%) |