Table 1 Patient characteristics and factors associated with cardiac dysfunction at intensive care unit admission
Variables | All patients | Cardiac dysfunction | No cardiac dysfunction | Odds ratio | 95% CI | P value |
|---|---|---|---|---|---|---|
n = 198 | n = 102 | n = 96 | ||||
Male gender | 130 (65.7%) | 70 (68.6%) | 60 (62.5%) | 1.31 | 0.72–2.36 | 0.36 |
Age | 67 (53–77) | 73.5 (60–79) | 58.5 (45–72) | 1.04 | 1.02–1.06 | < 0.0001 |
< 50 years | 31 (15.7%) | 8 (7.8%) | 23 (24.0%) | 0.27 | 0.11–0.64 | 0.003 |
50–70 years | 78 (39.4%) | 34 (33.3%) | 44 (45.8%) | 0.59 | 0.33–1.05 | 0.07 |
> 70 years | 89 (44.9%) | 60 (58.8%) | 29 (30.2%) | 3.30 | 1.83–5.94 | < 0.0001 |
SAPS II at ICU admission [9] | 37 (26–58) | 45 (30–65) | 32 (22–50) | 1.03 | 1.01–1.04 | 0.0001 |
OSF score at ICU admission [8] | 1 (0–2) | 1 (0–2) | 1 (0–1) | 1.62 | 1.21–2.16 | 0.0001 |
Comorbidities | ||||||
Chronic cardiac failure | 42 (21.2%) | 28 (27.5%) | 14 (14.6%) | 2.22 | 1.08–4.53 | 0.29 |
Chronic renal failure | 101 (51.0%) | 64 (62.7%) | 37 (34.7%) | 3.01 | 1.65–5.48 | 0.0003 |
Creatinine clearance, mL/minute | 48 (25–76) | 36 (11–65) | 50 (37–96) | 0.98 | 0.98–0.99 | 0.0006 |
Organ failure according to OSF score | ||||||
Cardiovascular | 50 (25.2%) | 36 (35.3%) | 14 (14.6%) | 3.74 | 1.57–6.39 | 0.001 |
Respiratory | 63 (31.8%) | 38 (37.2%) | 25 (26.0%) | 1.66 | 0.90–3.07 | 0.10 |
Renal | 50 (25.2%) | 34 (33.3%) | 16 (16.7%) | 2.48 | 1.26–4.89 | 0.008 |
Neurological | 43 (21.7%) | 27 (26.5%) | 16 (16.7%) | 1.78 | 0.88–3.57 | 0.10 |
Hepatic | 8 (4.0%) | 4 (3.9%) | 4 (3.1%) | 0.93 | 0.22–3.82 | 0.91 |
Clinically documented infection | 73 (36.9%) | 38 (37.2) | 35 (36.4%) | 0.99 | 0.55–1.79 | 0.98 |
NT-proBNP per 100 ng/L | 26.3 (4.7–73.0) | 57.2 (14.3–157.0) | 8.5 (1.9–35.6) | 1.01 | 1.01–1.02 | < 0.0001 |
Troponin (ng/mL) | 0.10 (0.02–0.44) | 0.16 (0.05–1.1) | 0.06 (0.01–0.21) | 1.39 | 1.03–1.88 | 0.03 |
ECG modifications | 92 (46.5%) | 75 (73.5%) | 17 (17.7%) | 12.90 | 6.51–25.59 | < 0.0001 |
C-reactive protein (mg/L) | 186 (78–332) | 234 (84–370) | 156 (74–223) | 1.003 | 0.98–1.01 | 0.3 |
Inotropic agents | 43 (21.7%) | 40 (39.2%) | 3 (3.1%) | 20 | 5.92–67.51 | < 0.0001 |
Vasopressive agents | 52 (26.3%) | 37 (36.3%) | 15 (15.6%) | 3.74 | 1.55–6.86 | 0.0013 |
Length of ICU stay, days | 3 (1–8) | 4 (1–10) | 3 (1–6) | 1.17 | 0.98–1.52 | 0.34 |
Length of hospital stay, days | 10 (3–21) | 11 (4.5–23.5) | 10 (3–20) | 1.01 | 0.99–1.01 | 0.39 |
ICU mortality | 47 (23.7%) | 35 (34.3%) | 12 (12.5%) | 3.65 | 1.76–7.59 | 0.0005 |
Hospital mortality | 72 (36.3%) | 52 (51%) | 20 (20.8%) | 3.95 | 2.1–7.4 | < 0.0001 |