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Figure 2 | Critical Care

Figure 2

From: Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats

Figure 2

Inhibitory avoidance task 30 days after cecal ligation and perforation (CLP). Animals were submitted to CLP or were placed in a sham-operated group. Thirty days after surgery, animals underwent the training test for an inhibitory avoidance task. Immediately after training, animals received a single injection of saline (SAL), epineohrine (EPI), naloxone (NAL), dexamethasone (DEX), or glucose (GLU), and animals were tested 24 hours after. Data are presented as median (interquartile range) of retention test latencies. *Significantly different between training and test, P < 0.05, Wilcoxon test. **Significantly different between NAL, GLU, EPI, or DEX and SAL in the test section, P < 0.05, Mann-Whitney test (Kruskal-Wallis chi-square 27.7, P < 0.001). #Significantly different between sham and CLP in the test section, P < 0.05, Mann-Whitney test (Kruskal-Wallis chi-square 30.8, P = 0.001).

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