Table 3 Cells and inflammatory parameters at baseline and before inhaled nitric oxide (INO) for responders and nonresponders

Leucocytes (10⁶/ml)

10.4 ± 4.4

1.6 ± 1.0^†

≤ 0.01

8.8 ± 2.4

0.9 ± 0.3* ^†

≤ 0.01

Neutrophils (%)

56 ± 12

65 ± 14

0.074

53 ± 10

48 ± 17*

0.45

Macrophage (%)

44 ± 12

34 ± 15

0.064

47 ± 10

51 ± 17*

0.45

Thrombocytes (10⁶/ml)

408 ± 77

185 ± 54^†

≤ 0.01

355 ± 61

175 ± 68^†

≤ 0.01

Proteins (mg/ml)

47 ± 6.0

33 ± 5.4^†

≤ 0.01

46 ± 6

34 ± 5^†

≤ 0.01

Endotoxin (pg/ml)

0

45 (3.8 to 296)^†

≤ 0.01

0 (0 to 4.5)

32 (0 to 392)^†

0.011

Endothelin-1 (pg/ml)

0

3.0 (1.8 to 8)^†

≤ 0.01

0

0.1 (0.1 to 8)

0.31

PGF_2α (pg/ml)

265 (236 to 327)

759 (356 to 1498)^†

≤ 0.01

218 (171 to 512)

380 (342 to 1632)^†

≤ 0.01

TXB₂ (pg/ml)

692 (530 to 778)

2881 (860 to 4504)^†

≤ 0.01

643 (574 to 821)

3883 (2286 to 5051)^†

≤ 0.01

6-keto-PGF_1α (pg/ml)

291 (232 to 323)

1023 (810 to 1560)^†

≤ 0.01

518 (274 to 899)

603 (557 to 1099)

0.33

LTB₄ (pg/ml)

28 (16 to 41)

372 (41 to 486)^†

≤ 0.01

38 (9 to 48)

274 (46 to 414)^†

≤ 0.01

TNFα (pg/ml)

15 (11 to 22)

18 (10 to 39)

0.083

12 (8 to 21)

10 (5 to 27)

1.0

IL-8 (ng/ml)

0

24(7.2 to 32)^†

≤ 0.01

0

4 (1.5 to 47)^†

0.03

Nitrates (nmol/ml)

212 (173 to 352)

183 (147 to 236)^†

≤ 0.01

183 (133 to 255)

173 (150 to 212)

0.58