Table 2 Cells, protein and inflammatory mediators from T0 (baseline) to T6

Leucocytes (10⁶/ml)

9.38 ± 3.85

2.02 ± 0.5*

1.44 ± 0.89*

0.97 ± 0.19*

1.13 ± 0.49*

1.25 ± 0.41*

1.86 ± 0.79

Neutrophils (%)

53 ± 11

27 ± 10*

34 ± 8.9*

43 ± 15

54 ± 15

73 ± 16*

75 ± 11*

Macrophage (%)

46 ± 11

71 ± 11*

65 ± 9.3*

55 ± 15

44 ± 16

27 ± 17*

23 ± 11*

Thrombocytes (10⁶/ml)

384 ± 73

245 ± 51*

208 ± 48*

172 ± 41*

177 ± 55*

178 ± 65*

191 ± 52*

Proteins (mg/ml)

47 (42 to 52)

39 (34 to 46)*

33 (29 to 36)*

28 (23 to 34)*

35 (26 to 38)*

27 (22 to 31)*

34 (29 to 35)*

Endotoxin (pg/ml)

0 (0 to 0.04)

758 (542 to 1,008)*

783 (525 to 1,004)*

200 (125 to 755)*

85 (27 to 413)*

12 (5 to 73)*

2.3 (0.3 to 11)

Endothelin-1 (pg/ml)

0.1

5.0 (4.0 to 6.0)*

5.0 (5.0 to 6.5)*

5.0 (4.5 to 6.5)*

3.0 (2.0 to 7.5)*

4.5 (4 to 6.5)*

0.6 (0.1 to 8.8)*

PGF_2α (pg/ml)

225 (167 to 344)

1,011 (859 to 1,216)*

1,301 (766 to 1,690)*

1,439 (971 to 1,708)*

387 (355 to 1513)*

1,028 (868 to 1,531)*

1,224 (333 to 1,562)*

TXB₂ (pg/ml)

687 (581 to 793

3,110 (2,617 to 3,546)*

2,824 (2,120 to 3,287)*

2,409 (2,129 to 3,110)*

4,103 (1,521 to 4,986)*

2,107 (1,648 to 2,430)*

3,150 (891 to 4,002)*

6-keto-PGF_1α (pg/ml)

294 (260 to 518)

749 (548 to 1778)

1,301 (899 to 1,658)*

732 (613 to 1341)

973 (716 to 1,504)*

464 (332 to 771)

877 (534 to 1,747)*

LTB₄ (pg/ml)

36 (23 to 46)

42 (22 to 210)

69 (24 to 225)

48 (29 to 266)

52 (42 to 423)

70 (43 to 187)

240 (42 to 463)

TNFα (pg/ml)

17 (11 to 22)

53 (21 to 120)*

29 (5 to 52)

34 (14 to 69)

15 (10 to 38)

26 (0.5 to 60)

3.5 (2.0 to 9.5)

IL-8 (ng/ml)

0

2.0 (0 to 63)

117 (108 to 127)*

116 (104 to 126)*

31 (27 to 46)

39 (19 to 52)

6 (2 to 21)

Nitrates (nmol/ml)

211 (162 to 309)

151 (139 to 174)*

135 (114 to 172)*

133 (119 to 149)*

189 (147 to 237)

140 (120 to 157)*

190 (173 to 240)