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Figure 1 | Critical Care

Figure 1

From: Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury

Figure 1

Levels of endothelin-1 and interleukin-8 compared with the increase or decrease of PaO2/FiO2. (a) Level of the endothelin-1 (ET-1) concentration (pg/ml) compared with the increase or decrease of PaO2/FiO2 (mmHg). All five animals exposed twice to inhaled nitric oxide decreased their ET-1 concentration level when changing from responder to nonresponder. (b) Level of IL-8 (ng/ml) compared with the increase or decrease of PaO2/FiO2 (mmHg). Levels of IL-8 decreased from response at the first exposure to nonresponse at the second exposure. Each symbol represents one animal; open symbol, first inhaled nitric oxide exposure; filled symbol, second exposure of the same animal with the same symbol.

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Critical Care

ISSN: 1364-8535