From: Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury
Drug
Normal renal function
Acute kidney injury
End-stage renal disease
Imipenem
130 ml/minute [55–58]
90 to 95 ml/minute [8, 59]
50 ml/minute [8, 60, 61]
Meropenem
45 to 60 ml/minute [62–64]
40 to 60 ml/minute [65, 66]
30 to 35 ml/minute [63, 64]
Vancomycin
40 ml/minute [67]
15 ml/minute [7]
5 ml/minute [68, 69]