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Table 1 Definition of classes and levels of evidence used in AHA recommendations

From: Clinical review: Critical care management of spontaneous intracerebral hemorrhage

Class I

Conditions for which there is evidence for and/or general agreement that the procedure or treatment is useful and effective

Class II

Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment

Class IIa

Weight of evidence or opinion is in favor of the procedure or treatment

Class IIb

Usefulness/efficacy is less well established by evidence or opinion

Class III

Conditions for which there is evidence and/or general agreement that the procedure or treatment is not useful/effective and in some cases may be harmful

Level of Evidence A

Data derived from multiple randomized trials

Level of Evidence B

Data derived from a single randomized trial or non-randomized trials

Level of Evidence C

Expert Opinion or case studies

  1. From [10].