Table 1 Clinical data of patient groups
From: Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis
Critically ill non-septic n = 10 | Severe sepsis n = 16 | p | |
|---|---|---|---|
Age | 61 +/- 5 | 56 +/- 4 | ns |
APACHE II score at inclusion | 12 +/- 1 | 26 +/- 2 | < 0.05 |
SAPS II score at inclusion | 23 +/- 2 | 57 +/- 4 | < 0.01 |
SOFA score at inclusion | 3 +/- 1 | 15 +/- 1 | < 0.001 |
Mechanically ventilated at inclusion (n) | 6 | 16 | |
Vasopressor treatment at inclusion (n) | 0 | 13 | |
Antibiotic treatment at inclusion (n) | 8 | 16 | |
Steroid dose* 3 mg/kg/24hours (n) | 0 | 8 | |
Serum interleukin-6 at inclusion (pg/ml) | 20.77 +/- 13.37 | 4304 +/- 2466 | < 0.001 |
Serum procalcitonin at inclusion (μg/l) | 0.25 +/- 0.18 | 39.38 +/- 23.56 | < 0.001 |
White blood cell count at inclusion (G/l) | 11.94 +/- 1.17 | 14.94 +/- 3.09 | ns |
Lymphocyte count at inclusion (G/l] | 1.47 +/- 0.19 | 0.88 +/- 0.24 | < 0.05 |