Table 3 Haemodynamic parameters of endotoxaemic rats. art = arterial; BE = base excess; ENHA = erythro-9-[2-hydroxyl-3-nonyl]-adenine; LPS = lipopolysaccharide; pCO2 = partial pressure of carbon dioxide; pHCO3- = bicarbonate; pO2 = partial pressure of oxygen; SO2 = oxygen saturation. Data are mean ± standard error of the mean.
Parameter | Group | Time (minutes) | ||
|---|---|---|---|---|
| Â | Â | 0 | 60 | 120 |
art. SO2 | Control | 94.5 ± 0.7 | 97.2 ± 0.5 | 95.5 ± 1.0 |
|  | LPS | 96.3 ± 0.8 | 97.4 ± 0.5 | 97.2 ± 0.3 |
|  | LPS + EHNA | 94.4 ± 0.5 | 92.4 ± 4.3 | 91.3 ± 5.6 |
art. PO2 | control | 83.4 ± 4.4 | 86.7 ± 3.7 | 88.3 ± 2.8 |
|  | LPS | 95.1 ± 9.5 | 107.1 ± 9.4 | 99.7 ± 4.2 |
|  | LPS + EHNA | 75.7 ± 2.3 | 89.5 ± 5.3 | 86.6 ± 6.9 |
art. PCO2 | control | 47.2 ± 1.4 | 41.3 ± 1.7 | 40.2 ± 1.1 |
|  | LPS | 42.8 ± 1.6 | 37.1 ± 1 | 35.0 ± 0.8 |
|  | LPS + EHNA | 49.5 ± 1 | 35.8 ± 3.9 | 34.0 ± 2.4 |
art. HCO3 - | control | 26.9 ± 0.5 | 24.5 ± 1.0 | 24.1 ± 0.5 |
|  | LPS | 25.3 ± 1.0 | 22.8 ± 0.6 | 18.6 ± 1.0 |
|  | LPS + EHNA | 28.2 ± 0.5 | 21.3 ± 3.4 | 18.7 2.5 |
art. PH | control | 7.37 ± 0.01 | 7.40 ± 0.01 | 7.39 ± 0.01 |
|  | LPS | 7.38 ± 0.01 | 7.40 ± 0.01 | 7.35 ± 0.02 |
|  | LPS + EHNA | 7.36 ± 0.01 | 7.28 ± 0.12 | 7.31 ± 0.07 |
art. BE | control | 1.4 ± 0.6 | 0.2 ± 1.0 | 0.2 ± 0.4 |
|  | LPS | 0.5 ± 0.9 | -1.1 ± 0.7 | -5.8 ± 1.3 |
|  | LPS + EHNA | 2.4 ± 0.6 | -5.3 ± 5.9 | -6.6 ± 3.7 |