Skip to main content

Table 1 Incidence, mortality, and criteria for acute kidney injury in patients with burns

From: Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study

Reference

Year

Years of study; population

AKI

AKI mortality

Criterion of AKI

Davies, et al. [8]

1979

1958–1979; >1,064 patients admitted

28 (<2.6%)

24 (86%)

Renal replacement therapy

Davies, et al. [9]

1994

1991; 18 burn units

15 (<1%)

12 (80%)

Renal replacement therapy

Leblanc, et al. [10]

1997

1987–1994; 970 patients admitted

16 (1.6%)

13 (82%)

Renal replacement therapy

Holm, et al. [11]

1999

1994–1998; 328 patients, 34% TBSA%

48 (15%)

41 (85%)

Renal replacement therapy

Tremblay, et al. [12]

2000

1995–1998; 353 patients admitted

12 (3.4%)

6 (50%)

Renal replacement therapy

Schiavon, et al. [13]

1988

1988; 20 patients, 44% TBSA%

4 (20%)

4 (100%)

Serum creatinine raised >133 μmol/L above value on admission

   

0

 

Renal replacement therapy

Saffle, et al. [7]

1993

1987–1990; 529 patients, 16% TBSA%

50 (10%)

23 (46%)

Thermal Injury Organ Failure Score (moderate: serum creatinine >222 μmol/L)

   

4 (0.8%)

4 (100%)

Renal replacement therapy

Sheridan, et al. [14]

1998

1989–1994; 56 patients who died

37 (68%)

-

Serum BUN ≥100 and creatinine ≥3.5 or urine output ≤500 mL/day

Jeschke, et al. [15]

1998

1966–1997; 5,000 children admitted

60 (1.2%)

44 (73%)

Oliguria (<0.5 mL/kg per hour for >36 hours), serum urea nitrogen/creatinine ratio <20, serum creatinine >177 μmol/L

   

34 (0.7)

28 (82%)

Renal replacement therapy

Chrysopoulo, et al. [16]

1999

1981–1998; 1,404 patients, TBSA% >30%

76 (5.4%)

67 (88%)

Three of these four: oliguria (<350 mL/36 hours), BUN/creatinine ratio <20, serum creatinine >177 μmol/L, and dialysis

   

67 (4.8%)

61 (91%)

Renal replacement therapy

Kim, et al. [17]

2003

2000; 147 patients, 60% TBSA%

28 (19%)

28 (100%)

Serum creatinine >177 μmol/L

   

3 (2.0%)

3 (100%)

Renal replacement therapy

Mustonen and Vuola [22]

2008

1988–2001; 238 patients, 31% TBSA%

93 (39.1%)

41 (44%)

Serum creatinine >120 μmol/L

   

32 (13%)

20 (62%)

Renal replacement therapy

Cumming, et al. [6]

2001

1998–1999; 85 patients, 30% TBSA%

3 (3.5%)

 

MODS (3–4: serum creatinine >350 μmol/L)

Cooper, et al. [18]

2006

1999–2001; 42 patients, 35% TBSA%

3 (7.1%)

 

MODS (3–4: serum creatinine >350 μmol/L) or oliguria

Coca, et al. [19]

2007

1998–2003; 304 patients, 27% TBSA%

81 (27%)

23 (28%)

RIFLE

    

(73%)

Renal replacement therapy

Lopes, et al. [20]

2007

2004–2006; 126 patients, 24% TBSA%

45 (36%)

21 (47%)

RIFLE

   

11 (8.7%)

 

Renal replacement therapy

  1. The table shows number of patients who had acute kidney injury (AKI) according to the criteria in the rightmost column; the percentage is the incidence of AKI among the study population. AKI mortality is the number of patients who died among those with AKI, with the percentage referring to mortality among the AKI patients. When available, incidence and outcome of renal replacement therapy are shown in the table, together with the result from the primary AKI criteria. Percentage burned of total body surface area (TBSA%) is the mean of the study group. When a TBSA% limit for inclusion was reported instead, it is shown in this table as 'TBSA% >%'. BUN, blood urea nitrogen; MODS, Multiple Organ Dysfunction Score; RIFLE, the increasing severity classes Risk, Injury, and Failure and the two outcome classes Loss, and End-stage renal disease.
Back to article page

Critical Care

ISSN: 1364-8535