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Table 1 28-Day all-cause mortality in TFPI-treated and placebo-treated patients

From: Beyond antibiotics in severe community-acquired pneumonia: the role and rationale for tissue factor pathway inhibition

 

Overall

INR ≥1.2

Placebo

TFPI

P

Positive blood culture

   n

257

278

 

   Total (%)

29.4

31.6

0.054

   Mortality (%)

35.4

27.7

 

Positive other

   n

387

370

 

   Total (%)

44.3

42.0

0.94

   Mortality (%)

35.1

35.4

 

Negative culture/not done

   n

230

232

 

   Total (%)

26.3

26.4

0.02

   Mortality (%)

30.0

40.1

 
  1. Presented are 28-day all-cause mortality rates in TFPI and placebo-treated patients with positive blood cultures, other documented infections, and negative culture or undocumented infections. INR, international normalized ratio; TFPI, Tissue factor pathway inhibitor.