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Table 2 Insulin therapy and control of blood glucose levels.

From: Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial

Variable Standard treatment (N = 250) Intensive treatment (N = 254) P value †
Administration of insulin (%) 118 (47) 246 (97) < 0.001
Insulin dose (IU/day) * 12.5 ± 32.8 52.4 ± 53.3 < 0.001
Morning blood glucose (mg/dl) ‡ – Median. (Interquartile range) 148
122 to 180
117
101 to 140
< 0.001
Minimal blood glucose (mg/dl) – Median. (Interquartile range) 122
105 to 143
82
72 to 94
< 0.001
Maximal blood glucose (mg/dl) – Median. (Interquartile range) 172
141 to 215
162
140 to 193
< 0.001
Median blood glucose (mg/dl) – Median. (Interquartile range) 149
124.5 to 180
120
109.5 to 134
< 0.001
Number of blood glucose measurement per day * 5.9 ± 4 13 ± 5.5 < 0.001
Number of patients in which morning median blood glucose was in their preset range (%) 43 (17.2) 100 (39.4) < 0.001
Hypoglycaemia ≤ 40 mg/dl (%) 2 (0.8) 21 (8.3) < 0.001
  1. * Values presented as mean ± SD. Hypoglycaemia are number of patients with at least one episode over total number of patients per group.
  2. † P values were determined wit the use of Student's t-test, Mann-Whitney test or Chi-square test as appropriate.
  3. ‡ To convert the values for glucose to millimoles per litre, multiply by 0.05551.