Table 4 Processed EEG and physiological variables, and RSS score 2 minutes before opiate boli
Variable | Indication | P | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | 0: left blank/missing | 1: patient asks | 2: agitation, nurse thinks of pain | 3: agitation, objective signs of pain | 4: anticipated pain (surgical) | 5: anticipated pain (nursing) | 6: to reduce sedatives | 7: comment | Â |
N | 60 | 39 | 60 | 56 | 16 | 73 | 9 | 49 | Â |
Response entropy | 73 (27 to 97) | 94 (35 to 98 | 53 (30 to 96 | 36 (25 to 63 | 28 (19 to 34 | 32 (25 to 81 | 17 (11 to 25 | 81 (33 to 96 | < 0.001 |
State entropy | 61 (25 to 87) | 81 (25 to 84) | 40 (24 to 87) | 30 (22 to 56) | 24 (18 to 29) | 28 (23 to 71) | 15 (10 to 19) | 65 (31 to 83) | < 0.001 |
BIS-Index | 66 (45 to 92) | 77 (62 to 93) | 62 (43 to 82) | 51 (40 to 59) | 49 (40 to 52) | 53 (42 to 73) | 46 (40 to 56) | 54 (32 to 73) | < 0.001 |
RSS score | 4 (2 to 5) | 2 (2 to 3) | 3 (1 to 4) | 3 (2 to 4) | 5 (3 to 5) | 4 (3 to 4) | 4 (2 to 4) | 4 (2 to 5) | < 0.001 |
Heart rate (beats/minute) | 92 (81 to 102) | 90 (72 to 101) | 96 (90 to 107) | 100 (94 to 109) | 97 (90 to 110) | 93 (85 to 100) | 95 (93 to 100) | 86 (74 to 95) | < 0.001 |
etCO2 (mmHg) | 36 (33 to 55) | 34 (32 to 46) | 41 (34 to 50) | 48 (36 to 55) | 43 (41 to 49) | 41 (35 to 48) | 54 (47 to 56) | 34 (27 to 45) | < 0.001 |
FiO2 (%) | 41 (38 to 59) | 39 (38 to 53) | 44 (39 to 53) | 53 (41 to 57) | 46 (45 to 52) | 45 (39 to 53) | 58 (51 to 60) | 39 (34 to 48) | < 0.001 |
Respiratory rate (breaths/minute) | 14.0 (11.8 to 19.9) | 12.8 (10.0 to 19.0) | 16.8 (12.2 to 20.9) | 19.8 (16.6 to 22.0) | 16.7 (13.6 to 20.0) | 16.5 (12.0 to 19.8) | 18.3 (13.5 to 19.0) | 13.6 (12.0 to 18.0) | < 0.001 |
SpO2 (%) | 96 (93 to 98) | 96 (93 to 97) | 95 (94 to 98) | 95 (93 to 97) | 98 (96 to 98) | 96 (94 to 98) | 96 (94 to 97) | 95 (94 to 97) | 0.053 |
SBP (mmHg) | 111 (99 to 126) | 119 (104 to 146) | 113 (102 to 133) | 101 (91 to 113) | 94 (76 to 102) | 109 (96 to 120) | 65 (53 to 116) | 105 (99 to 116) | < 0.001 |
MBP (mmHg) | 69 (61 to 78) | 77 (71 to 83) | 70 (66 to 81) | 66 (62 to 73) | 56 (48 to 68) | 70 (62 to 75) | 51 (44 to 79) | 67 (62 to 74) | < 0.001 |
DBP (mmHg) | 51 (42 to 59) | 55 (48 to 59) | 53 (47 to 59) | 50 (45 to 54) | 38 (28 to 44) | 51 (43 to 58) | 34 (34 to 43) | 50 (47 to 55) | < 0.001 |