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Table 9 Performance of various values of PetCO2 and duration of CPR for prediction of survival in patients with shockable initial rhythm in cardiac arrest

From: Partial pressure of end-tidal carbon dioxide successful predicts cardiopulmonary resuscitation in the field: a prospective observational study

PetCO2 Cut-off (kPa [mmHg]) n Min-max (kPa [mmHg]) Mean ± SD (kPa [mmHg]) Sensitivity (%) Specificity (%) PPV (%) NPV (%) AUROC (95% CI)
Initial ≤1.3 (10) 71 0.0–10 (0.0–1.3) 5.3 ± 1.9 (0.69 ± 0.35) 100 34 40 100 0.73 (0.67–0.78)
  >1.3 (10 233 10.1–65.4 (1.4–8.7) 19.5 ± 6.8 (2.59 ± 1.07)      
0–10 minute (average) ≤1.7 (12.8) 91 0.3–1.7 (2,5–12.8) 0.99 ± 0.36 (7.5 ± 2.1) 100 43 44 100 0.82 (0.78–0.87)
  >1.7 (12.8) 213 1.8–4.8 (12.9–36.1) 2.86 ± 0.76 (21.8 ± 5.2)      
10 minute ≤1.6 (12.1) 82 0.3–1.6 (2.3–12.1) 1.04 ± 0.41 (7.6 ± 3.4) 100 39 42 100 0.82 (0.78–0.87)
  >1.6 (12.1) 222 1.7–5.8 (12.2–43.6) 3.24 ± 0.93 (24.1 ± 7.1)      
11–15 minute (average) ≤1.6 (12.1) 93 0.4–1.6 (3.3–12.2) 0.99 ± 0.28 (7.4 ± 2.3) 100 44 45 100 0.78 (0.73–0.83)
  >1.6 (12.1) 211 1.8–5.5 (12.3–41.4) 3.22 ± 0.74 (24.4 ± 4.9)      
15 minute ≤1.9 (14.3) 94 0.2–1.9 (1.9–14.3) 1.25 ± 0.41 (7.9 ± 2.9) 100 45 45 100 0.78 (0.73–0.83)
  >1.9 (14.3) 210 2.0–7.7 (14.4–57.9) 3.73 ± 0.98 (27.8 ± 7.1)      
20 minute ≤1.5 (11.3) 93 0.3–1.5 (2.8–11.3) 0.95 ± 0.26 (7.2 ± 2.1) 100 44 45 100 0.78 (0.72–0.83)
  >1.5 (11.3) 211 2.1–7.3 (11.4–54.9) 4.33 ± 1.11 (32.3 ± 7.8)      
Max ≤2.5 (18.8) 89 0.7–2.5 (0.7–18.8) 1.62 ± 0.39 (12.4 ± 3.3) 100 42 44 100 0.81 (0.76–0.86)
  >2.5 (18.8) 215 2.6–10.6 (18.9–79.7) 5.3 ± 1.48 (39.9 ± 11.5)      
Final ≤1.5 (11.3) 93 0.3–1.5 (2.7–11.3) 1.0 ± 0.32 (7.5 ± 3.1) 100 44 45 100 0.78 (0.73–0.83)
  >1.5 (11.3) 211 1.9–6.3 (11.4–47.4) 3.69 ± 0.94 (27.8 ± 6.9)      
  1. 'Shockable' was defined as ventricular fibrillation or tachycardia. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, restoration of spontaneous circulation; SD, standard deviation.